Extended Data Fig. 6: SGBs loss as measured by qPCR and cultutomics. | Nature Medicine

Extended Data Fig. 6: SGBs loss as measured by qPCR and cultutomics.

From: Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial

Extended Data Fig. 6

A. Heatmap representation of metagenomics and qPCR with Kendall score (n = 118 samples from n = 31 patients). B. Species lost post-FMT as determined by qPCR between non-responders and responders (n = 91 R and n = 13 NR for n = 28 patients), p-value calculated by Non-parametric Mann–Whitney U test (two-sided), data are presented as mean values ± SEM. C. Culturomics analysis of the number of species isolated from n = 4 patients at baseline (n = 4 samples) compared to post-FMT (n = 4 samples) p-value calculated by Non-parametric Mann–Whitney U test (two-sided), data are presented as mean values ± SEM. D. culturomics analysis of the number of bacteria initially present in the patient’s baseline sample and no longer detected in the post-FMT sample, p-value calculated by Non-parametric Mann–Whitney U test (two-tailed).

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