Extended Data Fig. 9: Gating for flow cytometry on patient PBMCs.

A. Detailed gating for CD45+ cells, B. Non-linear dimension reduction on cell populations across all patients was applied and displayed through UMAP using automatic annotation with Scyan Python module, based-on expression matrix of characteristic markers for main populations. C. Detailed gating for CD4+ T cell and D. detailed gating for CD8+ T cells.