Fig. 4: fMRI BOLD signal maps following intravitreal KIO-301 administration.
From: Intravitreal photoswitch therapy in advanced retinitis pigmentosa: a phase 1 open-label trial
Representative axial fMRI slices from three participants showing voxel-wise BOLD signal maps overlaid on structural images at baseline and post-treatment time points. Images are shown for one participant with NLP, one with BLP and one with CF vision at baseline. Colored voxels represent suprathreshold task-associated BOLD signal displayed relative to baseline under the same stimulus conditions. The inset illustrates the anatomical location of striate cortex (V1) and adjacent extrastriate cortex (V2/V3).
