Extended Data Fig. 5: Late-onset colon cancer patients are more likely to be obese than early-onset patients. | Nature Medicine

Extended Data Fig. 5: Late-onset colon cancer patients are more likely to be obese than early-onset patients.

From: Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure

Extended Data Fig. 5: Late-onset colon cancer patients are more likely to be obese than early-onset patients.The alternative text for this image may have been generated using AI.

A subset of 96 patients within the TCGA-COAD cohort had physical metrics available. A. Among 24 early-onset patients, 4 were classified as obese (BMI > 30 kg/m2), compared to 18 out of 72 late-onset patients. This provided a relative risk (RR) of 0.67 (95% confidence interval: 0.26-1.76) for obesity in early-onset colorectal cancer patients. B. The boxplots show the methylation risk score distribution among these 96 patients, including the median (center line), interquartile range (box), and whiskers extending to the most extreme values within 1.5×IQR; points beyond represent outliers. CI; Confidence Interval, RR; relative risk.

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