Extended Data Fig. 2: ORR by CTFI, prior LOT, prior Top1i chemotherapy exposure, and brain metastasis at study entry among patients in the 1.8 mg kg−1 cohort.

CTFI, chemotherapy free interval; CTx, chemotherapy; LOT, line of therapy; Mets, metastasis; ORR, objective response rate; Top1i, topoisomerase 1 inhibitor.