Extended Data Fig. 6: Impact of SEZ6 expression on PFS and OS among patients in the 1.8 mg kg−1 and 2.5 mg kg−1 dose cohorts, stratified by median SEZ6 cytomembrane H-score of 145 into low (n = 36) and high (n = 39) cohorts. | Nature Medicine

Extended Data Fig. 6: Impact of SEZ6 expression on PFS and OS among patients in the 1.8 mg kg−1 and 2.5 mg kg−1 dose cohorts, stratified by median SEZ6 cytomembrane H-score of 145 into low (n = 36) and high (n = 39) cohorts.

From: SEZ6-targeting antibody−drug conjugate ABBV-706 in advanced small cell lung cancer and solid tumors: a phase 1 trial

Extended Data Fig. 6: Impact of SEZ6 expression on PFS and OS among patients in the 1.8 mg kg−1 and 2.5 mg kg−1 dose cohorts, stratified by median SEZ6 cytomembrane H-score of 145 into low (n = 36) and high (n = 39) cohorts.The alternative text for this image may have been generated using AI.

HR, hazard ratio; NE, not estimable; PFS, progression free survival; OS, overall survival; SEZ6, seizure-related homolog 6.

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