Extended Data Fig. 10: 46Q overexpression accelerates translation and triggers stress response and quality control. | Nature Methods

Extended Data Fig. 10: 46Q overexpression accelerates translation and triggers stress response and quality control.

From: Global analysis of endogenous protein disorder in cells

Extended Data Fig. 10: 46Q overexpression accelerates translation and triggers stress response and quality control.The alternative text for this image may have been generated using AI.

a, Protein abundance of 46Q from Stage I to III in T, S and P fractions. b-c, Comparison of T-IIa and T-IIn, and S-IIa and S-IIn. Red dots denote proteins with higher abundance in IIa. d-f, Heatmap of cluster-A and cluster-D in T, S and P fraction (top); enrichment analysis of P/T/S-cluster-A (bottom). P value was calculated by Fisher’s Exact Test, and further adjusted by Benjamini-Hochberg procedure as the multi-test adjustment method.

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