Extended Data Fig. 10: Stability analysis of hAZFa in yeast and in mouse early embryos.
From: De novo assembly and delivery of synthetic megabase-scale human DNA into mouse early embryos
a, The ratio of strains containing the correct hAZFa constructs for 50, 100, 150, and 200 passages verified by PFGE. n = 3 biological replicates. Error bars, mean ± SD. b and c, The WGS coverage and IGV snapshot of hAZFa in mouse one-cell, two-cell, four-cell, and morula embryos. n = 2 biological replicates. d, The average depth of hAZFa in mouse one-cell, two-cell, four-cell, and morula embryos (average depth of each sample: ranging from 39.367 to 39.753). n = 2 biological replicates.
