Fig. 6: Transcriptional regulation of hAZFa in mouse early embryos.
From: De novo assembly and delivery of synthetic megabase-scale human DNA into mouse early embryos
a, Genome browser view showing RNA-seq signals of hAZFa genes in mouse early embryos compared to those of AZFa in human early embryos46 and homologous genes in wild-type mouse early embryos. b, Bar chart showing the DNA methylation of hAZFa (three biological replicates for one-cell and two-cell, and two biological replicates for four-cell). c, Genome browser view showing RNA-seq signals of whole hAZFa regions with or without 5-azadC (two-cell) and DMOG (four-cell and 12-hour delay) treatments. h, hours; TET, ten-eleven translocation.
