Extended Data Fig. 4: Gene-level performance comparison with evidence-assisted annotation pipelines across 12 model species. | Nature Methods

Extended Data Fig. 4: Gene-level performance comparison with evidence-assisted annotation pipelines across 12 model species.

From: Highly accurate ab initio gene annotation with ANNEVO

Extended Data Fig. 4: Gene-level performance comparison with evidence-assisted annotation pipelines across 12 model species.

ANNEVO achieved optimal performance in most species. ANNEVO demonstrates complete gene structure recovery (highest recall) that aligned with nucleotide-level performance. Across all 12 model species, ANNEVO achieves a 4% absolute improvement in F1 score over BRAKER3 and an 11% absolute improvement over the deep learning baseline Helixer.

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