Extended Data Fig. 2: Spatial domain-level differential expression analysis of spatially-resolved transcriptomics (SRT) data. | Nature Neuroscience

Extended Data Fig. 2: Spatial domain-level differential expression analysis of spatially-resolved transcriptomics (SRT) data.

From: An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus

Extended Data Fig. 2

Volcano plotting of pseudobulked differential expression (DE) analysis for each spatial domain, with log2 fold change on the x-axis and FDR adjusted, -log10 transformed p-values on the y-axis. Genes colored red pass both FDR and log2 fold change thresholds (FDR adjusted p-value < 0.01 and absolute value of log2 fold change > 1). Top DE genes are labeled. See Supplementary Table 2 for spatial domain abbreviations.

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