Extended Data Fig. 7: Association of plasma GFAP with tau PET according to MATSPO status after FDR correction.
From: Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease
Region-wise linear regression T-map (FDR-corrected for multiple comparisons at P < 0.05) showing the association of plasma GFAP levels with tau PET SUVR across cortical areas in MA-TSPO (left) and MA+TSPO (right) individuals. Regression models with standardized biomarker levels were adjusted for age, sex, and cognitive status. Abbreviations: FDR = false discovery rate; GFAP = glial fibrillary acidic protein; MA = microglial activation; PET = positron emission tomography; SUVR = standardized uptake value ratio; TSPO = translocator protein.
