Extended Data Fig. 6: Effect of REM sleep on SPW rate and amplitude.
From: A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep

We identified all episodes of REM sleep that were ‘sandwiched’ on either side by episodes of NREM sleep, and possibly preceded by IS. That is, we found all NREM1 → REM → NREM2 and NREM1 → IS → REM → NREM2 sequences. We then computed the change in mean within-subject, Z-scored SPW rate and amplitude from pre-REM (NREM1) to post-REM (NREM2). a, Left, the distribution of changes in NREM SPW amplitude from pre-to-post-REM sleep. Right, the same changes in SPW amplitude as a function of the sandwiched REM sleep bout’s duration. b, Same as a, but for SPW rate.