Extended Data Fig. 7: Comparison of FC results for high and low frequency Ca2+ activity and HbT.

a) Low frequency ( < 0.1 Hz) Ca2+ connectivity matrices, averaged across subjects, comparing connectivity during low NE ( < 30th percentile; left) and high NE ( > 70th percentile; middle). Right: Difference between the high and low NE (‘+’ indicates p < 0.05, two-sided linear mixed-effects model, comparisons between low and high NE were performed separately for each region pair, n = 123 sessions, 8 subjects). P-values are provided in figure source data. b-c) Same as (a) but for 0.1-0.5 Hz and 0.5-5 Hz frequency bands. d-e) Same as (a-b) but for HbT. f) Low frequency ( < 0.1 Hz) Ca2+ seed correlation maps, averaged across subjects, comparing connectivity during low NE and high NE for MOs, SSp-ll, and VISp regions (n = 8 subjects). g-h) Same as (f) but for 0.1-0.5 Hz and 0.5-5 Hz frequency bands. i-j) Same as (f-g) but for HbT.