Extended Data Fig. 2: Cryo-EM analysis of CaChs2 in apo, UDP-GlcNAc bound, nikkomycin Z bound, and polyoxin D bound states.
From: Structural basis for inhibition and regulation of a chitin synthase from Candida albicans
a, General flowchart for data processing. b, Representative micrographs for each dataset. The number of total micrographs in each dataset is shown in Extended Data Fig.3. c, Representative 2D classes. d, Local resolution maps. e, Euler angle distribution of the final reconstructions. f, The gold-standard Fourier shell correlation (FSC) curves for the final reconstructions. g, FSC curves of the refined models versus the corresponding full map (red) and half maps (green and blue).
