Extended Data Fig. 2: The TEI of RNAi targeting three endogenously expressed genes was not enhanced following the loss of DDX-19. | Nature Structural & Molecular Biology

Extended Data Fig. 2: The TEI of RNAi targeting three endogenously expressed genes was not enhanced following the loss of DDX-19.

From: A nuclear pore-anchored condensate enables germ granule organization and transgenerational epigenetic inheritance

Extended Data Fig. 2: The TEI of RNAi targeting three endogenously expressed genes was not enhanced following the loss of DDX-19.

WT and ddx-19(-) animals were subjected to oma-1 RNAi (a), mex-6 RNAi(b), and puf-5 RNAi (c) treatment. Animals from P0, F1, F2, F4, F6, and F8 generations were collected and total RNAs were extracted. Quantitative reverse transcription and PCR (qRT-PCR) were employted to detect the mRNA levels of oma-1, mex-6, or puf-5 mRNAs in the indicated generations. n = 3 biological replicates. Student’s t-test, two-tailed. Error bar, ±s.d. Source numerical data are available.

Source data

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