Extended Data Fig. 8: Ec78 retron precise editing. | Nature Structural & Molecular Biology

Extended Data Fig. 8: Ec78 retron precise editing.

From: Structural basis for retron co-option of anti-phage ATPase-nuclease

Extended Data Fig. 8

a. Schematic of Ec78 retron precise editing targeting an EMX1 site. b. Quantification of Ec78 retron precise editing in comparison with no reverse transcriptase control (No RT), in the absence (Ec78) or the presence (Ec78+inhib) of inhibitors, AZD7648 and PolQi2, and the same experiments with the Mestre-1531 retron (RT 1531) with the same inhibitors. Bars represent means ± standard deviations of two biological replicates.

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