Extended Data Fig. 2: Examples showcasing behaviors of RNAPII and cohesin chromatin complexes at CTCF anchoring and cohesin loading sites with and without actively transcribed gene promoters. | Nature Structural & Molecular Biology

Extended Data Fig. 2: Examples showcasing behaviors of RNAPII and cohesin chromatin complexes at CTCF anchoring and cohesin loading sites with and without actively transcribed gene promoters.

From: Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription

Extended Data Fig. 2

(a) The 2D contact maps of RNAPII ChIA-PET, cohesin ChIA-PET, CTCF ChIA-PET, and Hi-C data encompassing all possible interactions for LRCH1 and LPAR1 locus. (b) Similar to Fig. 2b, but at the TSS of PIEZO2 in concordance with CTCF/cohesin anchoring site and TCF4 TSS coinciding with the cohesin loading site. (c) Similar to panel a but for PIEZO2 and TCF4 loci related to Extended Data Fig. 2b. (d) Similar to panel a, but at the TSS of HIVEP1 gene and CTCF-free cohesin loading site without TSS shown in Fig. 2d.

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