Fig. 2: Atomic model of the CF.
From: Atomic models of the Toxoplasma cell invasion machinery
a, Cross-sectional view of the atomic model of a CF segment, with component proteins shown in distinct colors. Viewing angles for b, d, e and g are indicated. b, Close-up view of TgDCX bound at the intradimer interface on the microtubule lattice. c, Close-up view of human DCX (PDB 6RF2)39 bound at the interdimer interface on the microtubule lattice. d, Longitudinal view of a CF segment with 24-nm periodicity, showing component proteins in distinct colors. Atomic models of α,β-tubulin are hidden for clarity. e, Close-up view of T. gondii SAS6L linear array in the region indicated by dashed rectangles in d. f, Crystal structure of zebrafish SAS6 homodimer (PDB 2Y3W)41. g, Luminal view of the CF structure showing that C-terminal short helices of CF2 bind across the seam. h, External surface view of the seam between protofilaments 4 and 5. i, Cutaway view of the CF structure showing CIP3 penetrating through the tubulin wall.
