Fig. 1

An overview of the experimental and data analysis workflow. Schematic shows the collection of samples, sequencing procedures and downstream bioinformatic analyses. Samples from mice at 7 different time points (0 hours [M0h], 6 hours [M6h], 12 hours [M12h], 24 hours [M24h], 7 days [M7d], and 14 days [M14d] post-stroke) and Sham group (Sham) were collected from cerebral cortex for single-nucleus assay for transposase-accessible chromatin with high-throughput sequencing (snATAC-seq).