Fig. 3
Clustering and annotation of chromatin accessibility in the cerebral cortex of MCAO/R mice. (a) Clustering visualization and annotations of 9 clusters identified by snATAC-seq data. (b) UMAP visualization of cell type–specific gene activity scores. Each dot represents an individual cell colored by cluster assignment. (c) The genome browser view shows aggregated chromatin accessibility profiles of cell type-specific gene loci. (d) The bar plot displays representative enriched pathways specific to the cell types. (e) The stacked chart illustrates the composition of cell proportions in the cerebral cortex for seven different time points of MCAO/R and Sham group, with colours indicate the cell types. (f) GO enrichment pathway analysis of genes highly expressed at M24h in MG. (g) GO enrichment pathway analysis of genes highly expressed at M14d in MG.
