Table 3 Summary of the donor counts with defined neuropsychiatric symptoms.

From: Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution

Neuropsychiatric symptom

Type

NPS-present

NPS-absent

Group 1: Early insomnia

specific

93

676

Group 1: Middle insomnia

specific

73

694

Group 1: Late insomnia

specific

91

682

Group 1: Hypersomnia

specific

23

766

Group 1: Weight gain

specific

41

761

Group 1: Suicidal ideations

specific

91

717

Group 1: Delusional worthlessness

specific

53

746

Group 1: Worthlessness

specific

67

730

Group 1: Psychomotor retardation

specific

88

723

Group 1: Sleep/WeightGain/Guilt/Suicide

aggregated

316

519

Group 2: Weight loss

specific

401

401

Group 2: Decreased appetite

specific

415

386

Group 2: Psychomotor agitation

specific

438

390

Group 2: Loss of energy

specific

438

379

Group 2: Ruminations

specific

391

428

Group 2: WeightLoss/PMA

aggregated

678

160

Group 3: Dysphoria

specific

410

408

Group 3: Anhedonia

specific

357

454

Group 3: Depression: current to 2 weeks

specific

254

558

Group 3: Depression: current to 6 months

specific

268

541

Group 3: Depression: lifetime

specific

251

528

Group 3: Depression/Mood

aggregated

448

386

  1. For “aggregated” types of symptoms, a donor is classified as “NPS-present” if they exhibit at least one of the “specific” symptoms. Conversely, a donor is classified as “NPS-absent” if at least one “specific” symptom is marked “false” and no symptoms are marked “true.”