Fig. 3
From: A comprehensive database for identifying and interpreting ctDNA driver genes and variants in cancer
Performance evaluation of geMERlb and statistics of the Prediction-Level dataset. (A) The proportions of CGC and HiConf genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across all 15 ctDNA datasets. (B) The proportions of CGC and HiConf genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across 15 individual ctDNA datasets. (C) The proportions of CGC and HiConf genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across all 33 TCGA datasets. (D) The proportions of CGC and HiConf genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across 33 individual TCGA datasets. (E) The proportions of ESCI genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across all 15 ctDNA datasets. (F) The proportions of ESCI genes identified by the geMERlb, ActiveDriverWGS, and DriverPower tools across 15 individual ctDNA datasets. (G) Statistics of TDGs and TDVs identified from 38 ctDNA mutation profiles. (H) Statistics of TDGs identified from the TCGA dataset.
