Table 1 Summary of Demographic and Clinical Characteristics by Histologic Subtype.
From: Matched MRI, Segmentations, and Histopathologic Images of Brain Metastases from Primary Lung Cancer
NSCLC | SCLC | Overall | ||
|---|---|---|---|---|
Non-Adenocarcinoma | Adenocarcinoma | |||
Number of biopsies/ scans (%) | 20 (18%) | 79 (71%) | 12 (11%) | 111 |
Size of dominant lesion (cm) (median; IQR) | 3.5 (2.9–4.1) | 3.3 (2.5–4.0) | 3.6 (1.6–4.5) | 3.3 (2.5–4.1) |
Number of patients | 18 | 74 | 11 | 103 |
Sex | ||||
Male (%) | 9 (50%) | 27 (36%) | 7 (64%) | 43 (42%) |
Female (%) | 9 (50%) | 47 (64%) | 4 (36%) | 60 (58%) |
Age at BM Dx (years) (median; IQR) | 65.5 (58–71.5) | 66 (61–72) | 69 (63–74) | 66 (60.5–72) |
KPS at BM Dx (median; IQR) | 80 (70–80) | 75 (60–80) | 70 (70–90) | 70 (60–85) |
ECM Present at BM Dx (%) | 14 (78%) | 48 (65%) | 7 (64%) | 69 (67%) |
Num. BM at Dx (median ± IQR) | 2 (1–4) | 2 (1–4) | 5 (1–5.5) | 2 (1–5) |
EGFR + (%) | 0 (0%) | 12 (16%) | 0 (0%) | 12 (12%) |
ALK + (%) | 0 (0%) | 1 (1%) | 0 (0%) | 1 (1%) |
PD-L1 + (%) | 5 (28%) | 16 (22%) | 0 (0%) | 21 (20%) |
