Fig. 4
From: Light sheet microscopy imaging dataset of CAR-T-cell-mediated cytotoxicity
Quantitative Analysis and Composition of Multi-Channel Imaging Data. (a) Comparison of photobleaching between confocal microscopy and our system. (b) Quantitative analysis of the photobleaching rate. (c) Comparison of morphology between normal cells and dasatinib-treated cells. (d) Graph of the IS area. We collected 419 biologically independent samples in 13 high-throughput experiments (n = 419). (e) Graph of actin flow speed. n = 419. (f) Graph of the mortality rate of Nalm6 cells labeled with SYTOX blue. Points represent individual CAR-T cells. #: dasatinib-treated group, *p < 0.05, **p < 0.01, ***p < 0.001. Scale bar, 5 μm.
