Table 1 Significantly up-regulated proteins after intravitreal injection of conbercept.

655884547

FLT1

vascular endothelial growth factor receptor 1

3.85

3.32

2.57

18.35

3.46

6.73

655833765

MKRN2

probable E3 ubiquitin-protein ligase makorin-2 isoform X5

2.10

1.57

2.68

6.63

2.99

4.52

655855155

NFKBIZ, Mail

NF-kappa-B inhibitor zeta isoform X2

4.04

1.57

3.08

6.36

7.89

1.35

291405684

YPEL2

protein yippee-like 2

1.04

2.71

3.27

3.64

3.32

2.54

655826988

LOW QUALITY PROTEIN: 39 S ribosomal protein L20, mitochondrial-like

3.61

1.11

3.40

3.20

2.92

3.28

655841362

KLHDC3

kelch domain-containing protein 3

1.20

3.44

2.80

3.08

3.78

1.35

655879793

DLGAP3

LOW QUALITY PROTEIN: disks large-associated protein 3

1.14

1.63

2.57

3.05

1.83

1.54

655878481

RC3H2

roquin-2 isoform X4

1.97

1.95

1.56

2.99

1.58

1.86

655846130

BCAN

brevican core protein

3.23

3.07

1.97

2.80

2.96

2.45

655834754

RBM15B

putative RNA-binding protein 15B

1.60

1.68

2.87

2.80

3.38

3.77

291389567

ZFC3H1

zinc finger C3H1 domain-containing protein

2.41

2.29

1.50

2.69

1.76

1.31

655600655

VPS13A

vacuolar protein sorting-associated protein 13 A

1.20

1.57

1.88

2.56

1.79

1.35

315360675

EPT1, SELI

*ethanolaminephosphotransferase 1

1.20

1.57

1.89

2.53

1.96

1.35

655901171

maestro heat-like repeat-containing protein family member 1

2.26

1.68

1.89

2.52

1.21

1.65

655837568

RNA-binding protein 48-like

1.43

2.11

1.80

2.39

1.45

1.96

655866221

DNAJB12

LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12

1.62

2.12

2.29

2.34

1.40

1.49

129270090

CRYAA

*alpha-crystallin A chain

1.88

1.00

1.79

2.33

1.88

1.19

655787703

CMTM4

CKLF-like MARVEL transmembrane domain-containing protein 4

1.14

1.22

1.71

2.20

2.00

1.16

655834907

BAP1

ubiquitin carboxyl-terminal hydrolase BAP1

1.26

1.01

2.74

2.18

2.50

3.44

655882768

CRYBB1

beta-crystallin B1

1.93

1.28

2.14

2.12

2.02

1.55

655862947

GATM

LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial

1.20

1.57

1.77

2.09

3.17

1.35

291416535

UVSSA

UV-stimulated scaffold protein A, partial

1.22

1.37

1.70

2.07

1.10

1.53

655883513

LOW QUALITY PROTEIN: carbonyl reductase [NADPH] 1-like

2.08

2.00

1.84

2.04

1.82

1.59

655896223

FAM118A

protein FAM118A

1.79

1.43

2.42

2.03

2.04

1.55

655850611

retinal-specific ATP-binding cassette transporter-like

1.73

1.95

2.20

2.00

2.02

1.88

655739906

BAZ2A

LOW QUALITY PROTEIN: bromodomain adjacent to zinc finger domain protein 2 A

2.10

1.49

1.64

1.96

1.67

1.89

126723630

LGALS3

*galectin-3

1.35

2.01

1.46

1.94

2.22

1.65

291387457

SRA1

steroid receptor RNA activator 1

1.10

1.46

1.32

1.93

1.81

2.39

655846332

GBA

glucosylceramidase isoform X2

2.26

1.65

1.66

1.86

1.65

1.36

655857145

BMPR1B

bone morphogenetic protein receptor type-1B isoform X2

2.35

2.57

4.93

1.85

5.11

2.57

655872717

ABCA5

ATP-binding cassette sub-family A member 5 isoform X2

2.16

1.55

2.17

1.83

2.27

2.05

655752526

CDK17

cyclin-dependent kinase 17

2.17

1.57

1.42

1.76

2.34

1.35

655771130

SAMD4B

protein Smaug homolog 2

1.20

1.57

2.13

1.76

1.95

1.35

655858544

PCDH10

protocadherin-10 isoform X2

1.50

2.18

1.72

1.67

1.59

1.23

655842878

CEP57L1

centrosomal protein CEP57L1 isoform X5

1.21

1.55

1.33

1.66

1.38

3.59

655605232

SORBS2

sorbin and SH3 domain-containing protein 2 isoform X9

1.61

2.24

2.23

1.60

1.12

1.84

655841271

TREML2

trem-like transcript 2 protein

9.55

1.57

2.51

1.59

2.81

1.35

291400631

ATPase inhibitor, mitochondrial-like

1.71

2.09

2.14

1.58

1.94

4.75

655727731

LETMD1

LETM1 domain-containing protein 1 isoform X2

2.53

2.27

1.79

1.57

1.83

1.35

291406313

MAPT

microtubule-associated protein tau isoform X11

5.27

1.50

3.98

1.48

2.58

4.30

291399405

MRTO4

mRNA turnover protein 4 homolog

1.36

1.20

2.30

1.45

1.22

1.59

655890274

OGG1

N-glycosylase/DNA lyase

1.86

1.57

1.92

1.38

1.88

2.89

291410889

PGER6

prostaglandin-E(2) 9-reductase

1.24

2.20

1.84

1.37

1.11

1.88

655835184

PXK

PX domain-containing protein kinase-like protein isoform X4

1.13

1.67

2.08

1.27

2.33

1.10

655601008

APOA1

apolipoprotein A-I isoform X1

1.11

2.85

1.09

1.24

1.34

1.31

655864723

ARPP19

cAMP-regulated phosphoprotein 19

1.14

1.40

1.22

1.20

1.22

2.06

655875742

PCSK1N

proSAAS

1.24

1.76

1.75

1.17

1.83

2.05

291405564

ASIC2

acid-sensing ion channel 2

1.59

1.68

2.17

1.15

1.14

1.02

147903853

ATP2A1, ATP2A3 SERCA1a

*sarcoplasmic/endoplasmic reticulum calcium ATPase 1

2.09

1.08

1.25

1.14

1.11

1.28

291398822

PARS2

probable proline–tRNA ligase, mitochondrial

1.75

1.58

2.15

1.11

1.40

1.06