Table 5 RNA-Seq: GO: Biological Process and Co-expression analysis.
GO Term | Bonferroni q-value |
|---|---|
GO: Biological Process | |
DEHP - Total | |
cotranslational protein targeting to membrane | 1.01E-19 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.79E-16 |
translational initiation | 2.84E-15 |
peptide biosynthetic process | 6.43E-14 |
EE2 - Total | |
small molecule biosynthetic process | 2.27E-10 |
lipid biosynthetic process | 3.87E-09 |
fatty acid metabolic process | 7.42E-08 |
cholesterol metabolic process | 9.28E-06 |
DEHP - Unique | |
protein targeting to ER | 2.86E-19 |
translation | 2.03E-16 |
rRNA processing | 5.46E-14 |
ribonucleoprotein complex biogenesis | 6.20E-11 |
EE2 - Unique | |
triglyceride metabolic process | 5.09E-01 |
purine nucleoside monophosphate metabolic process | 5.22E-01 |
response to dietary excess | 5.47E-01 |
neutral lipid metabolic process | 7.28E-01 |
Co-Expression | |
DEHP - Total | |
Genes up-regulated through activation of mTORC1 complex. | 6.79E-14 |
Genes involved in cholesterol homeostasis. | 6.58E-12 |
EE2 - Total | |
Genes down-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples. | 3.12E-05 |
Genes encoding proteins involved in metabolism of fatty acids. | 4.65E-04 |
DEHP - Unique | |
Molecular timetable composed of 162 time-indicating genes | |
(182 probes) in the peripheral (liver) clock. | 2.49E-12 |
Genes up-regulated in liver from mice transgenic for SREBF1 or SREBF2 [GeneID = 6720, 6721] and down-regulated in mice lacking SCAP [GeneID = 22937]. | 4.78E-10 |