Table 3 The relation between expressions of AGE, RAGE, TGF- β1, TGF- β1 receptor, BDNF and TrkB with morphometric and biomechanical parameters.

From: Abnormal expressions of AGEs, TGF-β1, BDNF and their receptors in diabetic rat colon–Associations with colonic morphometric and biomechanical remodeling

Proteins

 

Linear regression equation

R value

F value

P value

AGE

Muc

Muc = 0.310 − (0.000440 * BW)

0.705

8.875

0.015

Muc = 0.0822 + (169.012 * Wt/BW)

0.622

5.68

0.041

Muc = −0.0868 + (0.230 * WH)

0.604

5.158

0.049

Muc = 0.00227 − (0.649 * Res-in)

0.565

4.216

0.07

Muc = 0.0944 + (0.000429 * OA)

0.561

4.144

0.072

Mus

Mus = 0.810 − (0.00145 * BW)

0.685

7.963

0.02

Mus = −0.360 + (5.096 * Wet-W)

0.6

5.059

0.051

Mus = 0.0453 + (585.792 * Wet-W/BW)

0.635

6.095

0.036

Mus = −0.484 + (0.745 * WH)

0.577

4.495

0.063

Mus = −0.291 + (0.0452 * WA)

0.8

15.991

0.003

Mus = 0.0868 + (1.426 * Res-out)

0.709

9.119

0.014

Mus = −0.0638 + (0.00237 * OA)

0.913

45.05

<0.001

Mus = 0.0322 + (0.185 * C-a)

0.768

12.932

0.006

Mus = 0.0823 + (0.00724 * L-a)

0.76

12.323

0.007

Sub

Sub = 0.300 − (0.000605 * BW)

0.738

10.787

0.009

Sub = −0.190 + (2.140 * Wt)

0.652

6.644

0.03

Sub = −0.0318 + (269.423 * Wt/BW)

0.756

11.997

0.007

Sub = −0.326 + (0.388 * WH)

0.778

13.792

0.005

Sub = −0.141 + (0.0176 * WA)

0.805

16.544

0.003

Sub = −0.00796 + (0.629 * Res-out)

0.81

17.168

0.003

Sub = −0.0239 + (0.000751 * OA)

0.75

11.557

0.008

Sub = 2.296 + (10.104 * C-a)

0.736

10.631

0.01

Sub = 5.462 + (0.384 * L-a)

0.707

8.983

0.015

RAGE

Muc

Muc = 0.254 − (0.000467 * BW)

0.658

6.864

0.028

Muc = −0.105 + (1.513 * Wt)

0.531

3.541

0.093

Muc = −0.00805 + (220.533 * Wt/BW)

0.714

9.352

0.014

Muc = −0.152 + (0.231 * WH)

0.533

3.572

0.091

Mus

Muc = 0.254 − (0.000467 * BW)

0.658

6.864

0.028

Sub = −0.358 + (4.020 * Wet-W)

0.645

6.414

0.032

Sub = −0.0981 + (579.748 * Wet-W/BW)

0.857

24.932

<0.001

Sub = −0.423 + (0.558 * WH)

0.59

4.794

0.056

Sub = −0.169 + (0.0261 * WA)

0.63

5.911

0.038

Sub = 0.00952 + (0.00109 * OA)

0.573

4.402

0.065

Sub = 0.0343 + (0.0967 * C-a)

0.547

3.849

0.081

Sub

Mus = 0.803 − (0.00139 * BW)

0.734

10.522

0.01

Mus = −0.207 + (4.076 * Wt)

0.536

3.637

0.089

Mus = 0.0675 + (566.304 * Wt/BW)

0.687

8.037

0.02

Mus = −0.0757 + (0.0307 * WA)

0.608

5.281

0.047

Mus = 0.0824 + (0.00159 * OA)

0.685

7.963

0.02

Mus = 0.0998 + (0.152 * C-a)

0.706

8.935

0.015

Mus = 0.185 + (0.00474 * L-a)

0.556

4.032

0.076

TGF-β1

Muc

Muc = 0.340 − (0.000623 * BW)

0.625

6.406

0.03

Muc = −0.00104 + (0.0804 * C-a)

0.66

7.718

0.02

Muc = 0.0278 + (0.00300 * L-a)

0.629

6.556

0.028

Mus

Mus = −0.0827 + (0.0268 * WA)

0.588

5.275

0.045

Mus = 0.0707 + (0.00137 * OA)

0.686

8.882

0.014

Mus = 0.0755 + (0.133 * C-a)

0.687

8.956

0.014

Mus = 0.145 + (0.00434 * L-a)

0.573

4.876

0.052

Sub

Sub = 0.275 − (0.000420 * BW)

0.519

3.682

0.084

Sub = 0.0148 + (242.305 * Wt/BW)

0.649

7.287

0.022

Sub = −0.187 + (0.287 * WH)

0.548

4.284

0.065

TGF-β1-R

Muc

Muc = 0.379 − (0.000613 * BW)

0.556

4.465

0.061

Muc = −0.194 + (2.630 * Wet-W)

0.565

4.68

0.056

Muc = −0.00310 + (357.749 * Wet-W/BW)

0.704

9.807

0.011

Muc = −0.284 + (0.409 * WH)

0.572

4.853

0.052

Muc = −0.111 + (0.0202 * WA)

0.637

6.817

0.026

Muc = 0.0671 + (0.611 * Res-out)

0.547

4.262

0.066

Muc = 0.0466 + (0.000775 * OA)

0.557

4.508

0.06

Mus

Mus = 0.664 − (0.00107 * BW)

0.713

10.343

0.009

Mus = 0.0640 + (487.180 * Wt/BW)

0.702

9.707

0.011

Mus = −0.0126 + (0.0225 * WA)

0.52

3.698

0.083

Mus = 0.0998 + (0.00125 * OA)

0.659

7.665

0.02

Mus = 0.136 + (0.102 * C-a)

0.554

4.425

0.062

Sub

Sub = 0.560 − (0.000764 * BW)

0.637

6.836

0.026

Sub = 0.113 + (387.673 * Wet-W/BW)

0.701

9.684

0.011

BDNF

Mus

Mus = 0.184 + (0.000773 * BW)

0.624

6.371

0.03

Mus = 0.879 − (3.124 * Wt)

0.597

5.539

0.04

Mus = 0.626 − (371.476 * Wt/BW)

0.65

7.334

0.022

Mus = 1.036 − (0.530 * WH)

0.66

7.734

0.019

Mus = 0.827 − (0.0272 * WA)

0.765

14.114

0.004

Mus = 0.606 − (0.00100 * OA)

0.641

6.99

0.025

Mus = 0.641 − (0.120 * C-a)

0.794

17.08

0.002

Mus = 0.558 − (0.00334 * L-a)

0.564

4.669

0.056

Sub

Sub = 0.612 + (1.212 * Res-in)

0.648

7.219

0.023

Sub = 0.420 − (0.00306 * L-a)

0.596

5.506

0.041

TrkB

Muc

Muc = −0.0381 + (0.000426 * BW)

0.534

3.981

0.074

Muc = 0.205 − (203.828 * Wt/BW)

0.554

4.434

0.061

Muc = 0.223 − (0.000727 * OA)

0.722

10.914

0.008

Mus

Mus = 0.720 − (2.218 * Wt)

0.498

3.303

0.099

Mus = 0.529 − (241.906 * Wt/BW)

0.498

3.297

0.099

Mus = 0.916 − (0.452 * WH)

0.662

7.79

0.019

Mus = 0.667 − (0.0182 * WA)

0.601

5.657

0.039

Sub

Sub = −0.00703 + (0.000863 * BW)

0.632

6.645

0.028

Sub = 0.456 − (352.306 * Wet-W/BW)

0.559

4.555

0.059

Sub = 0.665 + (1.558 * Res-in)

0.655

7.526

0.021

Sub = 0.414 − (0.760 * Res-out)

0.549

4.322

0.064

Sub = 0.482 − (0.00122 * OA)

0.709

10.133

0.01

  1. Notes: Muc, mucosa; Mus, muscle; Sub, submucosa; BW, body weight; Wt, wet weight per unit length; Wt/BW, Wt to BW ratio; WH, wall thickness; WA, Wall area; Res-in, inner residual strain; Res-out, Outer residual strain; OA, opening angle, C-a, circumferential constant a; L-a, longitudinal constant a.
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