Table 3 Cytotoxicity of Compounds 13, 17 and 18.

From: Isolation, Structure Elucidation, and Absolute Configuration of Germacrane Isomers from Carpesium divaricatum

compounds

IC50 (μM)

HeLa

LoVo

BGC-823

MCF-7

13

7.60 ± 0.54

7.81 ± 0.25

12.68 ± 0.42

>50

17

5.76 ± 0.74

8.00 ± 0.20

13.68 ± 0.63

>50

18

4.72 ± 0.13

7.31 ± 0.21

11.67 ± 0.25

>50

cis-platin

7.90 ± 0.23

13.03 ± 1.49

15.34 ± 0.35

16.38 ± 1.41

  1. Values were mean ± SD.
  2. Cis-platin, positive control.
  3. Cell lines: HeLa: cervical cancer, LoVo: colon cancer, BGC-823: stomach cancer, and MCF-7: breast cancer.
Back to article page