Correction to: Scientific Reports https://doi.org/10.1038/srep09463, published online 30 March 2015
This Article contains errors.
In Figure 1,
“Collagen-induced arthritis (CIA) mouse model”
should read:
“Collagen-induced arthritis (CIA) rat model”
In addition, in Figure 4A the panel showing the inflamed paw of the CIA group is incorrect.
Furthermore, the legend of Figure 4 contains an error where,
‘mice’
should read:
‘rats’
The correct Figure 4 and its accompanying legend appear below as Figure 1.
Effects of Wu-tou decoction (WTD) on severity of arthritis in collagen-induced arthritis (CIA) rats. (A) macroscopic evidence of arthritis such as erythema or swelling was markedly observed in vehicle-treated CIA rats, while dose of 3.8 g/(kg·day) WTD significantly attenuated arthritis severity in CIA rats; (B) Doses of 0.95~3.8 g/(kg·day) WTD significantly decreased the mean arthritis score in a dose-dependent manner compared with vehicle-treated CIA rats; (C) Doses of 0.95~3.8 g/(kg·day) WTD significantly decreased the arthritis incidence in a dose-dependent manner compared with vehicle-treated CIA rats; (D) Doses of 0.95~3.8 g/(kg·day) WTD significantly decreased the percentage of arthritis limbs in a dose-dependent manner compared with vehicle-treated CIA rats; (E) Doses of 0.95~3.8 g/(kg·day) WTD significantly increased the time of arthritis first appeared compared with vehicle-treated CIA rats. Data are represented as the mean±S.D. (n=12). ‘#’, P<0.05, comparison with the normal control. ‘*’, ‘**’, and ‘***’, P<0.05, P<0.01, and P<0.001, respectively, comparison with the vehicle control.
Finally, in the Methods section under the subheading ‘Treatment and groups’,
“The dosage selection for WTD [3.8 μg/(kg·day)] was nearly equivalent to RA patient dosage daily (42 g/person/day).”
should read:
“The dosage selection for WTD [3.8 g/(kg·day)] was nearly equivalent to RA patient dosage daily (42 g/person/day).”
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Zhang, Y., Bai, M., Zhang, B. et al. Author Correction: Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation. Sci Rep 8, 15924 (2018). https://doi.org/10.1038/s41598-018-34061-y
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DOI: https://doi.org/10.1038/s41598-018-34061-y
