Figure 4

Ontogenetic gene expression levels of Bmp2, -4 and -16 in the cloudy catshark and the zebrafish. Plots show a developmental time course of gene expression levels (in FPKM values) of (A) cloudy catshark Bmp2, -4 and -16 genes (with standard errors derived from three biological replicates) and (B) zebrafish bmp2a, -2b, -4 and -16 genes. Sequencing data for the cloudy catshark was obtained in this study, while values for zebrafish were extracted from the literature (without replicates)46. Note the expression levels between the two species should not be compared since FPKM values are strongly influenced by the manners of sequence data acquisition, read trimming, and read mapping. Abbreviations: 1 K, 1000; hpf, hours post fertilization; dpf, days post fertilization.