Figure 4 | Scientific Reports

Figure 4

From: A Modified Collagen Dressing Induces Transition of Inflammatory to Reparative Phenotype of Wound Macrophages

Figure 4

Direct MCG treatment to human cultured macrophages induces IL-10 & VEGF production. THP-1 cells were differentiated to macrophage with PMA (20 ng/ml, 48 h). The differentiated cells were then treated with MCG (100 mg/ml; 72 h) (A) IL-10 (B) IL-4 and (C) VEGF protein released from THP-1 differentiated human macrophages measured by ELISA. Data are mean ± SEM (n = 4–5); *p < 0.05 compared to cells harvested from untreated THP-1 cells.

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