Table 1 Anthropometric and glyco-metabolic characteristic of patients and healthy controls.

From: Increased plasmatic NETs by-products in patients in severe obesity

 

Healthy Controls

Obese Patients

All

Male

Female

All

Male

Female

n = 128

55

21

34

73

24

49

Age, median (range)

37 (24–75)

36 (25–65)

41 (24–75)

45.5 (20–72)

46 (22–62)

45 (20–72)

Weight (kg)

67.8 ± 10.3

74.7 ± 8.4

62.8 ± 8.7*

127.2 ± 24.8##

147.4 ± 23.44

117.3 ± 19.0°°

Body mass index (Kg/m2)

24.1 ± 2.2

23.9 ± 1.9

24.1 ± 2.5

45.5 ± 7.5##

48.1 ± 7.3

44.2 ± 7.6 °

Waist circumference (cm)

90.5 ± 10.4

91.7 ± 11.7

89.6 ± 9.7

133.7 ± 18.7##

146.7 ± 16.6

127.3 ± 16.1°°

Hip circumference (cm)

100.8 ± 8.7

100.3 ± 8.9

101.3 ± 9

143.1 ± 15.6##

148.9 ± 17.4

140.3 ± 14.0

Visceral fat area (cm2)

n.d.

n.d.

n.d.

262.8 ± 73.7

325. 9 ± 47.8

233.2 ± 64.7°°

Fat mass (kg)

n.d.

n.d.

n.d.

58.7 ± 14.2

57.7 ± 13.4

60.9 ± 16.1

Fat-free mass (kg)

n.d.

n.d.

n.d.

66.4 ± 14.7

59.5 ± 8.2

81.9 ± 14.4°°

Systolic blood pressure (mmHg)

124 ± 19

123 ± 14

124 ± 21

138.7 ± 13.9##

143 ± 11

137 ± 15 °

Diastolic blood pressure (mmHg)

77 ± 10

80 ± 9

75 ± 10

85.8 ± 8.8##

87 ± 9

85 ± 8.9

Glycemia (mg/dl)

87.3 ± 8.7

90.6 ± 7.8

85.4 ± 8.3

101.7 ± 32.1#

118.2 ± 48.2

93.6 ± 15.1 °

Insulinemia (μIU/mL)

9.9 ± 6.1

8.7 ± 4.9

10.8 ± 7.06

20.1 ± 14.1##

25.2 ± 12.4

17.8 ± 14.4 °

HOMA-IR

2.1 ± 1.4

1.9 ± 1.2

2.23 ± 1.53

4.9 ± 3.5##

6.5 ± 3.0

4.1 ± 3.6°°

Tryglicerides (mg/dL)

112.9 ± 45.6

108.1 ± 43.5

116.4 ± 48.9

148.5 ± 90.2

180.8 ± 75.9

132.5 ± 93.2°°

Cholesterol (mg/dL)

179.8 ± 37.4

171.7 ± 24.8

183.5 ± 45.3

195.3 ± 37.7

183.4 ± 31.7

201.3 ± 39.4

LDL-c (mg/dL)

111.5 ± 33.8

103.5 ± 20.9

117.4 ± 40.8

113.9 ± 29.7

107.1 ± 29.1

117.2 ± 29.7

HDL-c (mg/dL)

48.7 ± 14.1

43.6 ± 14.4

52.4 ± 13.2

51.6 ± 13.6

40.2 ± 7.0

57.3 ± 12.4°°

ApoA-1 (mg/dL)

n.d.

n.d.

n.d.

147.8 ± 26.2

132.6 ± 17.9

156.9 ± 26.3°°

ApoB (mg/dL)

n.d.

n.d.

n.d.

99.3 ± 25.2

99.4 ± 23.0

99.3 ± 26.8

hs-CRP (µg/mL)

0.85 ± 1.07

0.71 ± 1.2

0.94 ± 1.02

19.7 ± 19.5##

11.4 ± 12.4

23.9 ± 21.2 °

MPO-DNA complexes (OD)

0.11 ± 0.06

0.09 ± 0.04

0.12 ± 0.075

0.46 ± 0.16##

0.45 ± 0.13

0.47 ± 0.17

  1. HOMA-IR, homeostasis model assessment for Insulin Resistance; LDL-c: low-density lipoprotein-cholesterol; HDL-c: high-density lipoprotein-cholesterol; ApoA-1: Apolipoprotein A1; ApoB: Apolipoprotein B; hs-CRP: high-sensitivity C-reactive protein. Results are expressed as mean ± SD. *P < 0.05 respect to healthy male subjects; °P < 0.05 respect to male obese patients; °°P < 0.001 respect to male obese patients; #P < 0.05 respect to healthy subjects; ##P < 0.001 respect to healthy subjects. P values were determined by Mann-Whitney and chi square test, 128 subjects were analyzed. n.d. = not determined.
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