Table 5 Main differences between the groups of patients that reduce and those that increase the plasma concentration of NETs byproducts after sleeve gastrectomy.

From: Increased plasmatic NETs by-products in patients in severe obesity

 

Patients that reduce

MPO-DNA

concentration after

sleeve gastrectomy

Patients that increase

MPO-DNA

concentration after

sleeve gastrectomy

P

N

40

33

 

MPO-DNA complexes before treatment (OD)

0.5 ± 0.13

0.42 ± 0.18

<0.05

MPO-DNA complexes after treatment (OD)

0.36 ± 0.14

0.66 ± 0.27

<0.001

MPO-DNA ratio (before/after)

1.63 ± 1.3

0.67 ± 0.22

<0.001

Age median yrs (range)

43.6 ± 11

43.6 ± 12.5

0.929

Males/females (n)

13/27

11/22

0.940

Smoke (n)

10

9

0.928

Diabetes mellitus (n)

4

5

0.505

Coronary heart disease (n)

1

2

0.446

Stroke (n)

0

2

0.114

History of thromboembolic events (n)

0

4

<0.05

Hypertension (n)

15

12

0.92

Hypercholesterolemia (n)

0

1

0.653

Thyroid disease (n)

6

5

0.516

COPD (n)

2

1

0.673

Body mass index variation (before-after, Kg/m2)

11.8 ± 5.1

11.2 ± 3.5

0.678

Weight variation (before-after, kg)

31.7 ± 13.8

29.9 ± 15.3

0.670

Subcutaneous fat variation (before-after, mm)

12.8 ± 9.3

8.3 ± 6.6

0.056

Triglycerides variation (before-after, mg/dL)

46.0 ± 72.51

35.7 ± 68.2

0.878

  1. COPD = chronic obstructive pulmonary disease. Results are expressed as mean ± SD. P values were determined by Mann-Whitney and chi square test, 73 obese patients were analyzed.