Table 7 Analysis of any association between general blood values and blood count and NETs (MPO-DNA complexes). WBC = white blood cells. 7a: P values were determined by Mann-Whitney; 7a: Correlations were determined by Spearman rank test.
From: Increased plasmatic NETs by-products in patients in severe obesity
A: General blood values and blood count of patients and healthy controls. | ||||||
|---|---|---|---|---|---|---|
Healthy Controls | Obese Patients | p | Before surgery | After surgery | p | |
N | 55 | 73 | — | 73 | 73 | |
Hematocrit (%) | 42.5 ± 4.0 | 41.7 ± 3.7 | 0.238 | 41.7 ± 3.7 | 41.6 ± 5.9 | 0.542 |
WBC (x103/μL) | 6.2 ± 1.3 | 7.7 ± 2.2 | <0.001 | 7.9 ± 1.8 | 7.0 ± 2.1 | <0.001 |
Neutrophils (x103/μL) | 3.5 ± 1.2 | 4.9 ± 1.6 | <0.001 | 4.9 ± 1.6 | 4.2 ± 1.9 | <0.001 |
Platelets (x103/μL) | 235 ± 50 | 260 ± 63 | <0.05 | 260 ± 63 | 245 ± 64 | <0.05 |
B: Correlations between the plasmatic concentration of MPO-DNA complexes and general blood values and blood count of the patients before sleeve gastrectomy | ||||||
Patients with severe obesity (n = 73) | Correlation coefficient respect to MPO-DNA complexes (ρ) before surgery | p | Correlation coefficient respect to MPO-DNA complexes (ρ) after surgery | p | ||
Hematocrit (%) | −0.034 | 0.779 | 0.217 | 0.076 | ||
WBC (x103/μL) | 0.102 | 0.392 | 0.077 | 0.517 | ||
Neutrophils (x103/μL) | 0.03 | 0.802 | 0.055 | 0.643 | ||
Platelets (x103/μL) | 0.219 | 0.065 | 0.044 | 0.719 | ||
