Table 2 Comparison of intraretinal layer thickness between pediatric and juvenile craniopharyngioma patients and healthy controls.

From: Inner and outer retinal layer thickness alterations in pediatric and juvenile craniopharyngioma

 

Patients (N = 18)

Controls (N = 20)

Estimates

Standard error

p-value*

Superior quadrant (μm)

RNFL

21.61 ± 5.55

32.03 ± 2.75

− 10.677

1.456

 < 0.0001

GCL

29.61 ± 6.08

46.60 ± 2.51

− 16.533

1.504

 < 0.0001

IPL

25.69 ± 3.16

37.38 ± 2.42

− 11.446

0.935

 < 0.0001

INL

41.89 ± 4.33

39.05 ± 3.32

3.364

1.202

0.2348

OPL

35.25 ± 9.57

34.70 ± 8.17

1.907

2.812

1.0000

ONL

61.36 ± 12.61

60.43 ± 10.87

0.966

3.975

1.0000

PRL

67.44 ± 2.00

67.03 ± 2.45

0.561

0.741

1.0000

Inferior quadrant (μm)

RNFL

23.72 ± 4.75

30.73 ± 1.95

− 7.238

1.198

 < 0.0001

GCL

31.94 ± 5.99

46.58 ± 2.49

− 14.373

1.523

 < 0.0001

IPL

26.75 ± 3.30

36.88 ± 2.25

− 9.761

0.908

 < 0.0001

INL

39.86 ± 4.71

38.88 ± 3.28

1.567

1.239

1.0000

OPL

30.42 ± 4.33

30.78 ± 5.54

− 0.220

1.690

1.0000

ONL

60.25 ± 10.32

60.3 ± 8.40

0.852

3.094

1.0000

PRL

66.11 ± 2.83

66.3 ± 2.86

0.020

0.957

1.0000

Nasal quadrant (μm)

RNFL

19.89 ± 3.98

34.05 ± 3.06

− 14.223

1.202

 < 0.0001

GCL

22.92 ± 5.48

47.33 ± 2.32

− 24.338

1.404

 < 0.0001

IPL

22.14 ± 3.15

37.50 ± 1.44

− 15.250

0.816

 < 0.0001

INL

40.86 ± 4.33

38.03 ± 2.84

3.332

1.155

0.1894

OPL

30.53 ± 3.37

29.53 ± 3.44

1.191

1.140

1.0000

ONL

67.53 ± 9.94

66.48 ± 6.27

1.786

2.686

1.0000

PRL

68.31 ± 2.12

67.88 ± 2.28

0.572

0.727

1.0000

Temporal quadrant (μm)

RNFL

17.22 ± 1.45

17.35 ± 1.03

− 0.135

0.420

1.0000

GCL

34.31 ± 9.16

44.45 ± 2.66

− 9.914

2.241

0.0026

IPL

32.33 ± 4.44

37.55 ± 1.90

− 4.975

1.116

0.0024

INL

36.61 ± 2.39

37.93 ± 2.48

− 0.816

0.669

1.0000

OPL

30.11 ± 4.59

30.53 ± 3.30

0.256

1.192

1.0000

ONL

61.78 ± 10.94

62.98 ± 6.54

− 0.884

3.026

1.0000

PRL

67.00 ± 2.57

67.65 ± 2.45

− 0.409

0.829

1.0000

  1. Significant values are indicated in bold.
  2. N numbers, RNFL retinal nerve fiber layer, GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer nuclear layer, PRL photoreceptor layer.
  3. *P-values obtained by linear regression were adjusted for age and SE and Bonferroni’s correction multiplied by 28.
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