Table 5 Factors linked to complete remission of T2DM 2 years after LSG.

From: Factors associated with resolution of type-2 diabetes mellitus after sleeve gastrectomy in obese adults

 

CR

n = 86

No CR

n = 140

p value

OR (95% CI)

Age (years)

 ≤ 45

76 (53.5%)

66 (46.5%)

 < 0.001

8.52 (4.07–17.83)

 > 45

10 (11.9%)

74 (88.1%)

 

1

Duration of DM

 ≤ 5 years

70 (64.8%)

38 (35.2%)

 < 0.001

11.74 (6.08–22.69)

 > 5 years

16 (13.6%)

102 (86.4%)

 

1

Insulin therapy

No

60 (42.9%)

80 (57.1%)

0.058

1.73 (0.98––3.06)

Yes

26 (30.2%)

60 (69.8%)

 

1

No. of oral hypoglycemics

Single

36 (69.2%)

16 (30.8%)

 < 0.001

5.58 (2.84–10.95)

Multiple

50 (28.7%)

124 (71.3%)

 

1

Preoperative BMI

 ≤ 40 kg/m2

33 (47.8%)

36 (52.2%)

0.045

1.80 (1.01–3.20)

 > 40 kg/m2

53 (33.8%)

104 (66.2%)

 

1

C-peptide (ng/mL)

    

 > 2.72

84 (56.8%)

64 (43.2%)

 < 0.001

49.88 (11.80–210.76)

 ≤ 2.72

2 (2.6%)

76 (97.4%)

 

1

Glycated hemoglobin (%)

 ≤ 6.5

22 (78.6%)

6 (21.4%)

 < 0.001

7.68 (2.97–19.86)

 > 6.5

64 (32.3%)

134 (67.7%)

 

1

HOMA-IR

 ≤ 4.6

76 (67.9%)

36 (32.1%)

 < 0.001

21.96 (10.26–45.97)

 > 4.6

10 (8.8%)

104 (91.2%)

 

1

  1. OR odds ratio, CI confidence interval, CR complete remission, BMI body mass index, HOMA-IR homeostatic model assessment of insulin resistance.