Table 2 Fixed effects of risk factors on baseline eGFR and changes of eGFR in patients with DM.
Fixed effects | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
Coefficient, ml/min/1.73m2 (95% CI) | P value | Coefficient, ml/min/1.73m2 (95% CI) | P value | Coefficient, ml/min/1.73m2 (95% CI) | P value | |
Effects on baseline eGFR (intercept) | ||||||
Sex (male) | − 5.47* (− 9.51 to − 1.43) | 0.008 | − 6.18* (− 10.27 to − 2.08) | 0.003 | − 4.61* (− 9.04 to − 0.18) | 0.04 |
Age (per 1 year older) | − 0.55* (− 0.69 to − 0.40) | < 0.001 | − 0.51* (− 0.66 to − 0.37) | < 0.001 | − 0.50* (− 0.66 to − 0.35) | < 0.001 |
BMI (per kg/m2) | 0.11 (− 0.11 to 0.33) | 0.32 | 0.08 (− 0.19 to 0.34) | 0.58 | ||
SBP (per 1 mmHg greater) | 0.02 (− 0.01 to 0.05) | 0.13 | 0.01 (− 0.03 to 0.05) | 0.57 | ||
Smoking (yes vs no) | 1.74 (− 1.85 to 5.33) | 0.34 | ||||
HbA1c (per 1%) | − 0.25 (− 0.93 to 0.43) | 0.47 | ||||
UPCR (per 10 mg/g) | 0.01 (-0.01 to 0.02) | 0.09 | ||||
Effects on changes of eGFR (slope) | ||||||
Sex (male) | − 0.17 (− 1.46 to 1.12) | 0.80 | − 0.20 (− 1.65 to 1.26) | 0.79 | 0.66 (− 1.20 to 2.52) | 0.49 |
Age (per 1 year older) | 0.01 (− 0.03 to 0.05) | 0.60 | 0.03 (− 0.02 to 0.07) | 0.22 | 0.01 (− 0.04 to 0.05) | 0.86 |
BMI (per kg/m2) | − 0.08 (− 0.17 to 0.01) | 0.05 | − 0.06 (− 0.16 to 0.04) | 0.25 | ||
SBP (per 1 mmHg greater) | − 0.01 (− 0.02 to 0.01) | 0.74 | 0.01 (− 0.02 to 0.03) | 0.83 | ||
Smoking (yes vs no) | − 0.53 (− 1.58 to 0.52) | 0.33 | ||||
HbA1c (per 1%) | − 0.06 (− 0.45 to 0.33) | 0.78 | ||||
UPCR (per 10 mg/g greater) | − 0.01* (− 0.02 to − 0.01) | < 0.001 | ||||
