Figure 4
The effects of TF rs3811647 and rs1799852 on plasma iron binding capacity and TSAT. (A) Transferrin rs3811647 All data (GG n = 720, GA n = 215, AA n = 24). ANOVA P for trend < 0.0001. Sample divided above and below median ferritin (< 26.9 ng/ml). High ferritin (GG n = 360, GA n = 108, AA n = 15). ANOVA P for trend < 0.0001. Low ferritin (GG n = 360, GA n = 107, AA n = 11). ANOVA P for trend ≤ 0.0001. rs1799852 All data (GG n = 839, GA n = 116, AA n = 4). ANOVA P for trend = NS. (B) UIBC rs3811647 All data (GG n = 985, GA n = 301, AA n = 28). ANOVA P for trend < 0.0001. Sample divided above and below median ferritin (< 26 ng/ml). High ferritin (GG n = 474, GA n = 147, AA n = 16). ANOVA P for trend < 0.0001. Low ferritin (GG n = 511, GA n = 154, AA n = 12). ANOVA P for trend < 0.0001. rs1799852 All data (GG n = 1139, GA n = 116, AA n = 9). ANOVA P for trend = NS. (C) TSAT rs3811647 All data (GG n = 720, GA n = 215, AA n = 24). ANOVA P for trend < 0.0001. Sample divided above and below median ferritin (< 26 ng/ml). High ferritin (GG n = 360, GA n = 108, AA n = 15).
