Table 2 Linear mixed-effects model for the change in cardiovascular biomarkers.
Variables | Baseline values | Change from the baseline (mean and 95% confidence intervals) | |||
|---|---|---|---|---|---|
6 months | P value | 12 months | P value | ||
baPWV (m/s) | |||||
HDx | 1.8 ± 0.7 | 0.1 (0 to 0.2) | 0.176 | 0 (− 0.1 to 0.2) | 0.518 |
Online-HDF | 1.9 ± 0.7 | − 0.1 (− 0.2 to 0) | 0.221 | 0.1 (0 to 0.3) | 0.046 |
Between-group difference | 0.2 (0 to 0.3) | 0.066 | − 0.1 (− 0.3 to 0.1) | 0.317 | |
LVEF (%) | |||||
HDx | 63.0 (57.0–69.0) | − 0.2 (− 2.5 to 2.1) | 0.860 | − 0.7 (− 3.1 to 1.7) | 0.561 |
Online-HDF | 63.0 (56.0–66.0) | 0.6 (–1.8 to 3.0) | 0.622 | − 0.6 (− 3.1 to 1.9) | 0.660 |
Between-group difference | − 0.8 (− 4.1 to 2.6) | 0.648 | − 0.1 (− 3.5 to 3.4) | 0.966 | |
LVMI (g/m2) | |||||
HDx | 111.3 (88.7–138.9) | − 36.1 (− 79.9 to 7.6) | 0.106 | − 39.2 (− 84.0 to 5.5) | 0.086 |
Online-HDF | 114.7 (102.2–142.9) | − 22.5 (− 69.8 to 24.8) | 0.351 | − 54.7 (− 103.2 to − 6.1) | 0.027 |
Between-group difference | − 13.4 (− 77.7 to 50.8) | 0.682 | 14.5 (− 51.4 to 80.4) | 0.666 | |
E/e′ | |||||
HDx | 12.0 (10.0–16.0) | 0.3 (− 1.0 to 1.7) | 0.628 | 0.4 (− 1.0 to 1.8) | 0.536 |
Online-HDF | 12.8 (10.0–14.8) | − 0.8 (− 2.3 to 0.6) | 0.274 | − 0.2 (− 1.7 to 1.3) | 0.815 |
Between-group difference | 1.2 (− 0.8 to 3.2) | 0.240 | 0.7 (− 1.4 to 2.7) | 0.516 | |
Coronary artery calcium score* | |||||
HDx | 295 (19–799) | 64.6 (0.7 to 128.5) | 0.048 | 154.9 (91.0 to 218.8) | < 0.001 |
Online-HDF | 268 (16–678) | 23.0 (− 43.1 to 89.1) | 0.496 | 36.6 (− 29.5 to 102.7) | 0.277 |
Between-group difference | 41.6 (− 50.3 to 133.6) | 0.375 | 118.3 (26.3 to 210.2) | 0.012 | |
