Table 2 Cardiovascular mortality in HD patients categorized by cigarette smoking status and occurrence of NIDDM nephropathy.

From: Paraoxonase 1 gene variants concerning cardiovascular mortality in conventional cigarette smokers and non-smokers treated with hemodialysis

Cause of death

Log-rank test P-value

HR (95% CI)

Wald test on 1 df, P-value

Adjusted P-valuea

HD cigarette smokers and HD non-smokers as a reference group

Cardiovascular

0.4

0.899 (0.699–1.156)

0.69, 0.4

0.699

All cardiac

0.2

0.836 (0.629–1.110)

1.53, 0.2

0.437

Cardiac related with CHD

0.4

0.842 (0.585–1.212)

0.86, 0.4

0.490

Cardiac non-related with CHD

0.4

0.819 (0.516–1.301)

0.71, 0.4

0.730

NIDDM nephropathy patients and non-diabetics as a reference group

Cardiovascular

0.01

1.348 (1.071–1.696)

6.47, 0.01

0.026

All cardiac

0.09

1.256 (0.961–1.640)

2.78, 0.1

0.143

Cardiac related with CHD

0.005

1.648 (1.154–2.354)

7.56, 0.006

0.016

Cardiac non-related with CHD

0.7

0.920 (0.602–1.405)

0.15, 0.7

0.765

NIDDM nephropathy smokers and non-diabetic smokers as a reference group

Cardiovascular

0.3

1.306 (0.820–2.079)

1.26, 0.3

0.432

All cardiac

0.5

1.186 (0.706–1.992)

0.41, 0.5

0.753

Cardiac related with CHD

0.05

1.938 (0.986–3.809)

3.69, 0.05

0.235

Cardiac non-related with CHD

0.6

0.813 (0.347–1.909)

0.23, 0.6

0.853

NIDDM nephropathy non-smokers and non-diabetic non-smokers as a reference group

Cardiovascular

0.02

1.360 (1.041–1.778)

5.08, 0.02

0.029

All cardiac

0.1

1.288 (0.940–1.765)

2.47, 0.1

0.116

Cardiac related with CHD

0.05

1.516 (0.989–2.323)

3.65, 0.06

0.050

Cardiac non-related with CHD

0.9

1.04 (0.638–1.695)

0.02, 0.9

0.898

  1. aAdjustment for age, gender, and HDL-cholesterol.