Table 4 Association between SNP rs11177 and clinical severity and pain analog scale in patients with hand OA.
Clinical scale | AA (N = 289) | AG (N = 578) | GG (N = 293) | χ2 | P | |
|---|---|---|---|---|---|---|
KL grade | KL-2 | 84 (29) | 273 (47) | 193 (66) | ||
KL-3 | 111 (38) | 187 (32) | 68 (23) | |||
KL-4 | 94 (33) | 118 (21) | 32 (11) | 84.96 | < 0.01 | |
Pain Analog Scale | Level 1: 1–3 | 26 (9) | 128 (22) | 107 (37) | ||
Level 2: 4–6 | 103 (36) | 314 (54) | 148 (51) | |||
Level 3: 7–9 | 160 (55) | 136 (24) | 38 (12) | 165.02 | < 0.01 | |