Table 1 characteristics of two primary cancer.
LCBC | BCLC | LCPC | PCLC | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall | sTPC | mTPC1 | mTPC2 | Overall | sTPC | mTPC1 | mTPC2 | Overall | sTPC | mTPC1 | mTPC2 | Overall | sTPC | mTPC1 | mTPC2 | |
No | ||||||||||||||||
343 | 118 | 143 | 82 | 1539 | 182 | 651 | 706 | 1181 | 374 | 538 | 269 | 7426 | 685 | 2969 | 3772 | |
Race | ||||||||||||||||
NHW | 314 | 113 | 124 | 77 | 1363 | 166 | 570 | 627 | 867 | 261 | 400 | 206 | 5422 | 484 | 2154 | 2784 |
NHB | 15 | 4 | 11 | 0 | 72 | 12 | 30 | 30 | 212 | 79 | 87 | 46 | 1252 | 128 | 528 | 596 |
NHA | 6 | 1 | 2 | 3 | 59 | 3 | 26 | 30 | 52 | 18 | 26 | 8 | 372 | 37 | 145 | 190 |
Hispanic | 8 | 0 | 6 | 2 | 43 | 1 | 25 | 17 | 48 | 16 | 23 | 9 | 358 | 36 | 132 | 190 |
Others | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 0 | 2 | 0 | 22 | 0 | 10 | 12 |
Sex | ||||||||||||||||
Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | Male | |
First diagnosis of year | ||||||||||||||||
> 2005 | 145 | 64 | 66 | 15 | 510 | 108 | 311 | 91 | 449 | 159 | 159 | 131 | 1653 | 154 | 518 | 981 |
1995–2005 | 119 | 32 | 49 | 38 | 596 | 47 | 222 | 327 | 366 | 89 | 176 | 101 | 3559 | 221 | 1205 | 2133 |
< 1995 | 79 | 22 | 28 | 29 | 433 | 27 | 118 | 288 | 366 | 126 | 203 | 37 | 2214 | 310 | 1246 | 658 |
Age of first diagnosis | ||||||||||||||||
Median | 70 | 71 | 71 | 67 | 69 | 71 | 71 | 65 | 67 | 71 | 67 | 62 | 68 | 70 | 70 | 67 |
IQR | 64–76 | 66–77 | 64–78 | 60–72 | 62–75 | 67–78 | 65–77 | 58–72 | 61–73 | 65–76 | 62–73 | 56–67 | 63–73 | 65–75 | 65–75 | 62–72 |
First insurance status | ||||||||||||||||
No | 1 | 1 | 0 | 0 | 3 | 1 | 1 | 1 | 6 | 1 | 4 | 1 | 17 | 2 | 9 | 6 |
Yes | 130 | 55 | 62 | 13 | 412 | 92 | 259 | 61 | 306 | 109 | 171 | 26 | 1587 | 242 | 944 | 401 |
Unknown | 212 | 62 | 81 | 69 | 1124 | 89 | 391 | 644 | 869 | 264 | 363 | 242 | 5822 | 441 | 2016 | 3365 |
First marital status | ||||||||||||||||
Single | 82 | 31 | 36 | 15 | 333 | 45 | 166 | 122 | 306 | 138 | 117 | 51 | 1568 | 159 | 675 | 734 |
Married | 254 | 86 | 102 | 66 | 1147 | 132 | 459 | 556 | 849 | 227 | 408 | 214 | 5146 | 446 | 1959 | 2741 |
Unknown | 7 | 1 | 5 | 1 | 59 | 5 | 26 | 28 | 26 | 9 | 13 | 4 | 712 | 80 | 335 | 297 |
First site | ||||||||||||||||
17 | 17 | 17 | 17 | 3 | 3 | 3 | 3 | 17 | 17 | 17 | 17 | 16 | 16 | 16 | 16 | |
First histology | ||||||||||||||||
8140 | 8140 | 8140 | 8140 | 8130 | 8130 | 8130 | 8130 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | |
First cancer stage | ||||||||||||||||
Localized | 124 | 18 | 59 | 47 | 1411 | 148 | 601 | 662 | 403 | 56 | 243 | 104 | 6448 | 502 | 2632 | 3314 |
Regional | 94 | 32 | 45 | 17 | 99 | 26 | 39 | 34 | 278 | 62 | 147 | 69 | ||||
Distant | 70 | 47 | 21 | 2 | 2 | 1 | 0 | 1 | 204 | 138 | 51 | 15 | 180 | 69 | 69 | 42 |
Unstaged | 55 | 21 | 18 | 16 | 27 | 7 | 11 | 9 | 296 | 118 | 97 | 81 | 798 | 114 | 268 | 416 |
First surgery | ||||||||||||||||
No | 140 | 74 | 61 | 5 | 51 | 7 | 24 | 20 | 403 | 254 | 131 | 18 | 4367 | 503 | 1947 | 1917 |
Yes | 199 | 41 | 81 | 77 | 1485 | 175 | 624 | 686 | 762 | 108 | 404 | 250 | 2966 | 159 | 987 | 1820 |
Unknown | 4 | 3 | 1 | 0 | 3 | 3 | 0 | 16 | 12 | 3 | 1 | 93 | 23 | 35 | 35 | |
First radiotherapy | ||||||||||||||||
No | 2 | 2 | 0 | 0 | 3 | 2 | 1 | 59 | 4 | 30 | 25 | |||||
Yes | 130 | 56 | 58 | 16 | 24 | 6 | 12 | 6 | 325 | 138 | 135 | 52 | 3053 | 177 | 1300 | 1576 |
Unknown | 211 | 60 | 85 | 66 | 1515 | 176 | 639 | 700 | 853 | 234 | 403 | 216 | 4314 | 504 | 1639 | 2171 |
Interval time (month) | ||||||||||||||||
Median | 21 | 1 | 25 | 100.5 | 55 | 2 | 31 | 117 | 21 | 1 | 26 | 104 | 62 | 2 | 31 | 108 |
IQR | 3–58 | 0–4 | 15–40 | 75–162 | 22–108 | 1–4 | 19–46 | 83–156 | 3–56 | 0–3 | 15–40 | 80–141 | 26–109 | 1–4 | 19–45 | 81–147 |
Secondary insurance | ||||||||||||||||
No | 1 | 1 | 0 | 0 | 5 | 0 | 3 | 2 | 3 | 2 | 1 | 34 | 4 | 16 | 14 | |
Yes | 174 | 53 | 72 | 49 | 852 | 93 | 348 | 411 | 401 | 89 | 200 | 112 | 4363 | 279 | 1438 | 2646 |
Unknown | 168 | 64 | 71 | 33 | 682 | 89 | 300 | 293 | 777 | 283 | 337 | 157 | 3029 | 402 | 1515 | 1112 |
Secondary marital status | ||||||||||||||||
Single | 88 | 32 | 36 | 20 | 422 | 44 | 184 | 194 | 297 | 128 | 111 | 58 | 2059 | 169 | 807 | 1083 |
Married | 230 | 80 | 95 | 55 | 1061 | 132 | 447 | 482 | 754 | 211 | 363 | 180 | 5088 | 488 | 2051 | 2549 |
Unknown | 25 | 6 | 12 | 7 | 56 | 6 | 20 | 30 | 130 | 35 | 64 | 31 | 279 | 28 | 111 | 140 |
Secondary diagnosis of year | ||||||||||||||||
> 2005 | 199 | 64 | 80 | 55 | 944 | 109 | 385 | 450 | 343 | 157 | 138 | 48 | 669 | 153 | 340 | 176 |
1995–2005 | 91 | 33 | 39 | 19 | 398 | 46 | 180 | 172 | 314 | 90 | 143 | 81 | 1961 | 217 | 1005 | 739 |
< 1995 | 53 | 21 | 24 | 8 | 197 | 27 | 86 | 84 | 524 | 127 | 257 | 140 | 4796 | 315 | 1624 | 2857 |
Age of secondary diagnosis | ||||||||||||||||
Median | 73 | 71 | 73 | 76 | 75 | 72 | 73 | 76 | 70 | 71 | 69 | 72 | 75 | 70 | 73 | 77 |
IQR | 67–80 | 66–77 | 66–80 | 70–82 | 69–80 | 67–78 | 68–80 | 70–82 | 65–76 | 65–76 | 65–75 | 67–77 | 69–80 | 65–75 | 68–78 | 72–82 |
Secondary site | ||||||||||||||||
3 | 3 | 3 | 3 | 17 | 17 | 17 | 17 | 16 | 16 | 16 | 16 | 17 | 17 | 17 | 17 | |
Secondary histology | ||||||||||||||||
8130 | 8130 | 8130 | 8130 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | 8140 | |
Secondary cancer stage | ||||||||||||||||
Localized | 283 | 98 | 120 | 65 | 288 | 54 | 112 | 122 | 824 | 204 | 389 | 231 | 1270 | 125 | 497 | 648 |
Regional | 21 | 11 | 6 | 4 | 277 | 37 | 130 | 110 | - | - | - | - | 1400 | 165 | 575 | 660 |
Distant | 3 | 2 | 0 | 1 | 753 | 66 | 319 | 368 | 83 | 39 | 30 | 14 | 3855 | 286 | 1584 | 1985 |
Unstaged | 36 | 7 | 17 | 12 | 221 | 25 | 90 | 106 | 274 | 131 | 119 | 24 | 901 | 109 | 313 | 479 |
Secondary surgery | ||||||||||||||||
No | 23 | 10 | 10 | 3 | 1131 | 118 | 467 | 546 | 846 | 279 | 390 | 177 | 5586 | 432 | 2206 | 2948 |
Yes | 320 | 108 | 133 | 79 | 389 | 62 | 177 | 150 | 304 | 78 | 137 | 89 | 1771 | 241 | 736 | 794 |
Unknown | 0 | 0 | 0 | 0 | 19 | 2 | 7 | 10 | 31 | 17 | 11 | 3 | 69 | 12 | 27 | 30 |
Secondary radiotherapy | ||||||||||||||||
No | 0 | 0 | 0 | 0 | 15 | 1 | 5 | 9 | 5 | 2 | 3 | 0 | 75 | 2 | 35 | 38 |
Yes | 12 | 7 | 2 | 3 | 568 | 55 | 245 | 268 | 355 | 59 | 190 | 106 | 2709 | 245 | 1155 | 1309 |
Unknown | 331 | 111 | 141 | 79 | 956 | 126 | 401 | 429 | 821 | 313 | 345 | 163 | 4642 | 438 | 1779 | 2425 |
Survival time since lung primary (month) | ||||||||||||||||
Mean | 53 | 11 | 52 | 160.5 | 7 | 11 | 8 | 6 | 66 | 9 | 70 | 167 | 7 | 11 | 8 | 7 |
IQR | 20–125 | 44–705 | 33–95 | 107–217 | 44–611 | 4–33 | 44–612 | 44–608 | 18–132 | 3–21.5 | 39–108 | 124–218 | 44–613 | 3–32 | 44–614 | 44–610 |
Major cause of cancer-related death | ||||||||||||||||
LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | LUAC | |
Major cause of noncancer-related death | ||||||||||||||||
HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | HD | |