Table 4 Saturation effect analysis of high-density lipoprotein cholesterol and total bone mineral density.

From: The correlation between high-density lipoprotein cholesterol and bone mineral density in adolescents: a cross-sectional study

Direct HDL cholesterol (mmol/L)

Male

Female

β (95% CI), P-value

β (95% CI), P-value

12–15 years old

 Fitting by the standard linear model

− 0.032 (− 0.052, − 0.012) 0.0022

− 0.012 (− 0.033, 0.009) 0.2507

 Fitting by the two-piecewise linear model

  

 Turn point of direct HDL cholesterol (mmol/L)

0.93

0.98

 < K, effect1

− 0.158 (− 0.312, − 0.004) 0.0450

0.104 (− 0.112, 0.320) 0.3463

 > K, effect2

− 0.030 (− 0.050, − 0.009) 0.0045

− 0.015 (− 0.036, 0.006) 0.1712

 The effect difference

0.128 (− 0.027, 0.283) 0.1066

− 0.119 (− 0.339, 0.101) 0.2906

 The predicted value of the equation at the folding point

0.983 (0.972, 0.995)

0.994 (0.983, 1.006)

 Log-likelihood ratio test

0.103

0.285

16–19 years old

 Fitting by the standard linear model

− 0.028 (− 0.054, − 0.002) 0.0342

− 0.019 (− 0.040, 0.002) 0.0780

 Fitting by the two-piecewise linear model

  

 Turn point of direct HDL cholesterol (mmol/L)

1.06

1.06

 < K, effect1

− 0.129 (− 0.216, − 0.041) 0.0042

− 0.232 (− 0.344, − 0.120) < 0.0001

 > K, effect2

− 0.009 (− 0.040, 0.021) 0.5480

− 0.003 (− 0.025, 0.020) 0.8228

 The effect difference

0.119 (0.020, 0.219) 0.0192

0.229 (0.111, 0.348) 0.0002

 The predicted value of the equation at the folding point

1.118 (1.108, 1.129)

1.058 (1.047, 1.068)

 Log-likelihood ratio test

0.018

 < 0.001

  1. All covariates were adjusted.