Table 4 Saturation effect analysis of high-density lipoprotein cholesterol and total bone mineral density.
Direct HDL cholesterol (mmol/L) | Male | Female |
|---|---|---|
β (95% CI), P-value | β (95% CI), P-value | |
12–15 years old | ||
Fitting by the standard linear model | − 0.032 (− 0.052, − 0.012) 0.0022 | − 0.012 (− 0.033, 0.009) 0.2507 |
Fitting by the two-piecewise linear model | ||
Turn point of direct HDL cholesterol (mmol/L) | 0.93 | 0.98 |
< K, effect1 | − 0.158 (− 0.312, − 0.004) 0.0450 | 0.104 (− 0.112, 0.320) 0.3463 |
> K, effect2 | − 0.030 (− 0.050, − 0.009) 0.0045 | − 0.015 (− 0.036, 0.006) 0.1712 |
The effect difference | 0.128 (− 0.027, 0.283) 0.1066 | − 0.119 (− 0.339, 0.101) 0.2906 |
The predicted value of the equation at the folding point | 0.983 (0.972, 0.995) | 0.994 (0.983, 1.006) |
Log-likelihood ratio test | 0.103 | 0.285 |
16–19 years old | ||
Fitting by the standard linear model | − 0.028 (− 0.054, − 0.002) 0.0342 | − 0.019 (− 0.040, 0.002) 0.0780 |
Fitting by the two-piecewise linear model | ||
Turn point of direct HDL cholesterol (mmol/L) | 1.06 | 1.06 |
< K, effect1 | − 0.129 (− 0.216, − 0.041) 0.0042 | − 0.232 (− 0.344, − 0.120) < 0.0001 |
> K, effect2 | − 0.009 (− 0.040, 0.021) 0.5480 | − 0.003 (− 0.025, 0.020) 0.8228 |
The effect difference | 0.119 (0.020, 0.219) 0.0192 | 0.229 (0.111, 0.348) 0.0002 |
The predicted value of the equation at the folding point | 1.118 (1.108, 1.129) | 1.058 (1.047, 1.068) |
Log-likelihood ratio test | 0.018 | < 0.001 |