Table 5 Optimization of reaction conditions in the presence of Fe3O4@SiO2@KIT-6@2-ATP@CuI catalyst.
From: Fe3O4@SiO2@KIT-6@2-ATP@CuI as a catalyst for hydration of benzonitriles and reduction of nitroarenes
Entry | Solvent | Catalyst (mg) | NaBH4 (mmol) | Time (min) | Yield (%)a |
|---|---|---|---|---|---|
1 | H2O | 10 | 5 | 40 | 82 |
2 | H2O | 15 | 5 | 40 | 84 |
3 | H2O | 20 | 5 | 40 | 92 |
4 | EtOH | 20 | 5 | 40 | 81 |
5 | H2O:EtOH | 20 | 5 | 40 | 79 |
6 | H2O | 20 | 4 | 40 | 83 |
7 | H2O | 20 | 3 | 40 | 75 |
8 | CH3CN | 20 | 5 | 40 | 31 |
9 | MeOH | 20 | 5 | 40 | 49 |
