Table 1 The effect of Hsp70 on the ion permeability of phospholipid bilayers.

From: A new look at Hsp70 activity in phosphatidylserine-enriched membranes: chaperone-induced quasi-interdigitated lipid phase

Lipid composition

Csc (μg/mL)

Ctr (μg/mL)

POPC

nf

5.5 ± 0.5

POPS

2.0 ± 0.5

3.5 ± 0.5

DOPS

nf

4.4 ± 0.4

DPhPS

2.0 ± 0.2

3.5 ± 0.3

  1. Csc the threshold concentration of Hsp70 required to appearance of step-like current fluctuations corresponding to single ion-permeable transmembrane pores, Ctr the threshold concentration of Hsp70 required to disintegrate lipid bilayers of appropriate composition, nf single pores were not observed.
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