Table 2 Baseline clinical characteristics of all the study subjects.

From: Role of miR-128-3p and miR-195-5p as biomarkers of coronary artery disease in Indians: a pilot study

Parameters

CAD (n = 89)

Controls (n = 35)

p-value

Age

55.90 ± 9.92

50.32 ± 8.25

0.002

Gender (male/female)

69/20

12/23

 < 0.0001

Height (in cm)

162.59 ± 7.03

158.60 ± 9.35

0.143

Weight (in kg)

67.35 ± 12.65

64.75 ± 10.31

0.750

BMI

25.27 ± 4.34

25.84 ± 4.14

0.359

Hypertension

61.5%

41.7%

0.148

Type 2 DM presence

46%

30.4%

0.225

Blood lipid profile

 

 Total cholesterol (mg/dl)

130.7 ± 44.16

174.27 ± 58.59

 < 0.005

 Triglyceride (mg/dl)

134.15 ± 34.96

141.14 ± 99.79

0.079

 LDL (mg/dl)

62.9 ± 35.1

103.62 ± 62.67

0.032

 HDL (mg/dl)

34.73 ± 8.44

44.8 ± 7.99

0.0002

 VLDL (mg/dl)

25.22 ± 7.73

28.71 ± 19.62

0.361

Medications & therapies

 

 Aspirin

95%

76.9%

0.088

 Statin

92.5%

53.8%

0.004

 Beta blockers

90%

46.1%

0.009

 Ace inhibitors

63.4%

15.4%

0.023

 Angiotensin receptor blockers

14.6%

30.8%

0.237

  1. *Data has been represented in the form of percentages and Mean ± SD. The statistical significance of the clinical parameters was analysed using non-parametric Mann–Whitney U test. Age, Gender, Total cholesterol, LDL, HDL, Statin, Beta blockers and Ace Inhibitors were significantly different between control subjects and the patients.