Table 3 Top three of biological processes, molecular functions, cellular components, and KEGG pathways (www.kegg.jp/kegg/kegg1.html).
Datasets | Biological processes | Molecular function | Cellular components | KEGG pathways |
|---|---|---|---|---|
GSE69252 | Inflammatory response (GO:0006954) Cellular response to cytokine stimulus (GO:0071345) Cytokine-mediated signaling pathway (GO:0019221) | Chemokine activity (GO:0008009) Chemokine receptor binding (GO:0042379) Cytokine activity (GO:0005125) | Secretory granule membrane (GO:0030667) Azurophil granule (GO:0042582) Vacuolar lumen (GO:0005775) | Cytokine–cytokine receptor interaction (map04060) Chemokine signaling pathway (map04062) Viral protein interaction with cytokine and cytokine receptor (map04061) |
GSE64610 | Inflammatory response (GO:0006954) Cellular response to lipopolysaccharide (GO:0071222) Cytokine-mediated signaling pathway (GO:0019221) | Cytokine activity (GO:0005125) Chemokine receptor binding (GO:0042379) Cytokine activity (GO:0005125) | Microvillus membrane (GO:0031528) Golgi membrane (GO:0000139) Cytoskeleton (GO:0005856) | Rheumatoid arthritis (map05323) Viral protein interaction with cytokine and cytokine receptor (map04061) Toll-like receptor signaling pathway (map04620) |
GSE63931 | Neutrophil chemotaxis (GO:0030593) Granulocyte chemotaxis (GO:0071621) Neutrophil migration (GO:1990266) | Chemokine activity (GO:0008009) Chemokine receptor binding (GO:0042379) Serine-type endopeptidase activity (GO:0004252) | Cytolytic granule (GO:0044194) Lysosome (GO:0005764) T cell receptor complex (GO:0042101) | Viral protein interaction with cytokine and cytokine receptor (map04061) Toll-like receptor signaling pathway (map04620) Chemokine signaling pathway |
GSE55664 | Natural killer cell mediated immunity (GO:0002228) Chemokine-mediated signaling pathway (GO:0070098) Cellular response to chemokine (GO: 1990869) | Chemokine activity (GO:0008009) Chemokine receptor binding (GO:0042379) CCR chemokine receptor binding (GO: 0048020) | Cytolytic granule (GO:0044194) Ficolin-1 rich granule membrane (GO:0101003) Ficolin-1 rich granule (GO:0101002) | Viral protein interaction with cytokine and cytokine receptor (map04061) IL-17 signaling pathway (map04657) Staphylococcus aureus infection (map05150) |
GSE42088 | Positive regulation of acute inflammatory response (GO:0002675) negative regulation of transcription from RNA polymerase II in response to stress (GO:0097201) positive regulation of fever generation (GO:0031622) | Protein kinase activator activity (GO:0030295) cAMP response element binding (GO: 0035497) Kinase binding (GO:0019900) | Macropinosome (GO:0044354) Pinosome (GO:0044352) Endocytic vesicle membrane (GO: 0030666) | TNF signaling pathway (map04668) Rheumatoid arthritis (map05323) IL-17 signaling pathway (map04657) |
GSE43661 | Heat acclimation (GO:0010286) Cellular heat acclimation (GO:0070370) Regulation of neuroblast proliferation (GO:1902692) | Chemokine activity (GO:0008009) Chemokine receptor binding (GO:0042379) C3HC4-type RING finger domain binding (GO:0055131) | Aggresome (GO:0016235) Cornified envelope (GO:0001533) Multivesicular body, internal vesicule (GO:0097487) | Legionellosis (map05134) Splicesome (map03040) Antigen processing and presentation (map04612) |