Table 3 Top three of biological processes, molecular functions, cellular components, and KEGG pathways (www.kegg.jp/kegg/kegg1.html).

From: An integrated bioinformatic analysis of microarray datasets to identify biomarkers and miRNA-based regulatory networks in leishmaniasis

Datasets

Biological processes

Molecular function

Cellular components

KEGG pathways

GSE69252

Inflammatory response (GO:0006954)

Cellular response to cytokine stimulus (GO:0071345)

Cytokine-mediated signaling pathway (GO:0019221)

Chemokine activity (GO:0008009)

Chemokine receptor binding (GO:0042379)

Cytokine activity (GO:0005125)

Secretory granule membrane (GO:0030667)

Azurophil granule (GO:0042582)

Vacuolar lumen (GO:0005775)

Cytokine–cytokine receptor interaction (map04060)

Chemokine signaling pathway (map04062)

Viral protein interaction with cytokine and cytokine receptor (map04061)

GSE64610

Inflammatory response (GO:0006954)

Cellular response to lipopolysaccharide (GO:0071222)

Cytokine-mediated signaling pathway (GO:0019221)

Cytokine activity (GO:0005125)

Chemokine receptor binding (GO:0042379)

Cytokine activity (GO:0005125)

Microvillus membrane (GO:0031528)

Golgi membrane (GO:0000139)

Cytoskeleton (GO:0005856)

Rheumatoid arthritis (map05323)

Viral protein interaction with cytokine and cytokine receptor (map04061)

Toll-like receptor signaling pathway (map04620)

GSE63931

Neutrophil chemotaxis (GO:0030593)

Granulocyte chemotaxis (GO:0071621)

Neutrophil migration (GO:1990266)

Chemokine activity (GO:0008009)

Chemokine receptor binding (GO:0042379)

Serine-type endopeptidase activity (GO:0004252)

Cytolytic granule (GO:0044194)

Lysosome (GO:0005764)

T cell receptor complex (GO:0042101)

Viral protein interaction with cytokine and cytokine receptor (map04061)

Toll-like receptor signaling pathway (map04620)

Chemokine signaling pathway

GSE55664

Natural killer cell mediated immunity (GO:0002228)

Chemokine-mediated signaling pathway (GO:0070098)

Cellular response to chemokine (GO: 1990869)

Chemokine activity (GO:0008009)

Chemokine receptor binding (GO:0042379)

CCR chemokine receptor binding (GO: 0048020)

Cytolytic granule (GO:0044194)

Ficolin-1 rich granule membrane (GO:0101003)

Ficolin-1 rich granule (GO:0101002)

Viral protein interaction with cytokine and cytokine receptor (map04061)

IL-17 signaling pathway (map04657)

Staphylococcus aureus infection (map05150)

GSE42088

Positive regulation of acute inflammatory response (GO:0002675)

negative regulation of transcription from RNA polymerase II in response to stress (GO:0097201)

positive regulation of fever generation (GO:0031622)

Protein kinase activator activity (GO:0030295)

cAMP response element binding (GO: 0035497)

Kinase binding (GO:0019900)

Macropinosome (GO:0044354)

Pinosome (GO:0044352)

Endocytic vesicle membrane (GO: 0030666)

TNF signaling pathway (map04668)

Rheumatoid arthritis (map05323)

IL-17 signaling pathway (map04657)

GSE43661

Heat acclimation (GO:0010286)

Cellular heat acclimation (GO:0070370)

Regulation of neuroblast proliferation (GO:1902692)

Chemokine activity (GO:0008009)

Chemokine receptor binding (GO:0042379)

C3HC4-type RING finger domain binding (GO:0055131)

Aggresome (GO:0016235)

Cornified envelope (GO:0001533)

Multivesicular body, internal vesicule (GO:0097487)

Legionellosis (map05134)

Splicesome (map03040)

Antigen processing and presentation (map04612)