Table 1 Comparison between reaction time and % yield of the target compounds in presence and absence of Fe2O3 nano catalyst using reflux and ultrasonic.

From: Catalyzed syntheses of novel series of spiro thiazolidinone derivatives with nano Fe2O3: spectroscopic, X-ray, Hirshfeld surface, DFT, biological and docking evaluations

Compound

With Fe2O3 nano-catalyst

Without Fe2O3 nano-catalyst

Reflux (yield %, time)

Ultrasonic (yield %, time)

Reflux (yield %, time)

Ultrasonic (yield %, Time)

A

(93%, 4h)

(80%, 1h)

(72%, 8h)

(69%, 2h)

B

(92%, 4h)

(90%, 1h)

(70%, 8h)

(71%, 2h)

C

(86%, 4h)

(80%, 1h)

(75%, 8h)

(72%, 2h)

D

(88%, 4h)

(90%, 1h)

(71%, 8h)

(70%, 2h)

E

(93%, 4h)

(89%, 1h)

(67%, 8h)

(66%, 2h)

F

(90%, 4h)

(83%, 1h)

(65%, 8h)

(61%, 2h)

G

(84%, 4h)

(84%, 1h)

(69%, 8h)

(69%, 2h)

H

(83%, 4h)

(80%, 1h)

(58%, 8h)

(56%, 2h)

I

(80%, 4h)

(83%, 1h)

(62%, 8h)

(64%, 2h)

J

(83%, 4h)

(90%, 1h)

(60%, 8h)

(61%, 2h)

K

(87%, 4h)

(79%, 1h)

(65%, 8h)

(61%, 2h)

L

(82%, 4h)

(78%, 1h)

(62%, 8h)

(59%, 2h)

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