Table 1 Clinical features of 80 patients with Guillain–Barré syndrome with and without hyponatremia.

From: Risk factors and outcome of hyponatremia in patients with Guillain–Barré syndrome

 

Patients with hyponatremia, (n = 18)

Patients without hyponatremia, (n = 62)

P-value

Age (years), mean ± SD

62.8 ± 17.3

44.8 ± 20.1

0.003

Male, n (%)

8 (44)

39 (63)

0.183

Urinary retention, n (%)

11 (61)

4 (6)

 < 0.0001

Hugh grade at admission

 1

0 (0)

4 (6)

 

 2

3 (17)

32 (52)

 

 3

0 (0)

6 (10)

 

 4

11 (61)

19 (31)

 

 5

4 (22)

1 (2)

 

Hugh grade at nadir

 1

0 (0)

4 (6)

 

 2

0 (0)

28 (45)

 

 3

2 (11)

8 (13)

 

 4

10 (56)

16 (26)

 

 5

6 (33)

5 (8)

 

 6

0 (33)

1 (2)

 

GBS subtype

 AIDP, n (%)

10 (56)

14 (23)

0.017

 AMAN, n (%)

5 (28)

22 (35)

0.778

 Equivocal, n (%)

3 (17)

26 (42)

0.057

 Sepsis, n (%)

6 (33)

2 (3)

0.001

Therapy

 IVIG, n (%)

17 (94)

53 (85)

0.442

 Steroid, n (%)

7 (39)

3 (5)

0.686

 Plasma exchange, n (%)

3 (17)

3 (5)

0.124

 Mechanical ventilator support, n (%)

6 (33)

5 (8)

0.013

 Hospitalization length of stay, mean ± SD

74.2 ± 34.6

26.2 ± 21.6

 < 0.0001

 Inability to walk independently at 6 months, n (%)

8 (44)

3 (5)

 < 0.001

  1. GBS Guillain–Barré syndrome, AIDP acute inflammatory demyelinating polyneuropathy, AMAN acute motor axonal neuropathy, IVIG intravenous immunoglobulin, SD standard deviation.